N-Myc–mediated epigenetic reprogramming drives lineage plasticity in advanced prostate cancer

Despite recent therapeutic advances, prostate cancer remains a leading cause of cancer-related death. A subset of castration-resistant prostate cancers become androgen receptor (AR) signaling independent and develop neuroendocrine prostate cancer (NEPC) features through lineage plasticity. These NEP...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Berger, Adeline, Brady, Nicholas J., Bareja, Rohan, Robinson, Brian, Conteduca, Vincenza, Augello, Michael A., Puca, Loredana, Ahmed, Adnan, Dardenne, Etienne, Lu, Xiaodong, Hwang, Inah, Bagadion, Alyssa M., Sboner, Andrea, Elemento, Olivier, Paik, Jihye, Yu, Jindan, Barbieri, Christopher E., Dephoure, Noah, Beltran, Himisha, Rickman, David S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715370/
https://ncbi.nlm.nih.gov/pubmed/31260412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI127961
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