N-Myc–mediated epigenetic reprogramming drives lineage plasticity in advanced prostate cancer

Despite recent therapeutic advances, prostate cancer remains a leading cause of cancer-related death. A subset of castration-resistant prostate cancers become androgen receptor (AR) signaling independent and develop neuroendocrine prostate cancer (NEPC) features through lineage plasticity. These NEP...

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Bibliografiset tiedot
Julkaisussa:J Clin Invest
Päätekijät: Berger, Adeline, Brady, Nicholas J., Bareja, Rohan, Robinson, Brian, Conteduca, Vincenza, Augello, Michael A., Puca, Loredana, Ahmed, Adnan, Dardenne, Etienne, Lu, Xiaodong, Hwang, Inah, Bagadion, Alyssa M., Sboner, Andrea, Elemento, Olivier, Paik, Jihye, Yu, Jindan, Barbieri, Christopher E., Dephoure, Noah, Beltran, Himisha, Rickman, David S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2019
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715370/
https://ncbi.nlm.nih.gov/pubmed/31260412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI127961
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