SLFN11 expression in advanced prostate cancer and response to platinum-based chemotherapy

Expression of the DNA/RNA helicase schlafen family member 11 (SLFN11) has been identified as a sensitizer of tumor cells to DNA damaging agents including platinum chemotherapy. We assessed the impact of SLFN11 expression on response to platinum chemotherapy and outcomes in patients with metastatic c...

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Pubblicato in:Mol Cancer Ther
Autori principali: Conteduca, Vincenza, Ku, Sheng-Yu, Puca, Loredana, Slade, Megan, Fernandez, Luisa, Hess, Judy, Bareja, Rohan, Vlachostergios, Panagiotis J., Sigouros, Michael, Mosquera, Juan Miguel, Sboner, Andrea, Nanus, David M., Elemento, Olivier, Dittamore, Ryan, Tagawa, Scott T., Beltran, Himisha
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7440143/
https://ncbi.nlm.nih.gov/pubmed/32127465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-19-0926
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