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Efficiency of bridging between related dose finding studies

The statistical problem of bridging is closely associated with the problem of heterogeneity in dose-finding studies. There are some distinctive features in the case of bridging which need to be considered if efficient estimation of the maximum tolerated dose (MTD) is to be accomplished. The case of...

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Udgivet i:C R Math
Hovedforfatter: O’Quigley, John
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714985/
https://ncbi.nlm.nih.gov/pubmed/31467599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.crma.2013.01.015
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