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Efficiency of bridging between related dose finding studies

The statistical problem of bridging is closely associated with the problem of heterogeneity in dose-finding studies. There are some distinctive features in the case of bridging which need to be considered if efficient estimation of the maximum tolerated dose (MTD) is to be accomplished. The case of...

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Detalles Bibliográficos
Publicado en:C R Math
Autor Principal: O’Quigley, John
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714985/
https://ncbi.nlm.nih.gov/pubmed/31467599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.crma.2013.01.015
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