Xenoantigen-Dependent Complement-Mediated Neutralization of Lymphocytic Choriomeningitis Virus Glycoprotein-Pseudotyped Vesicular Stomatitis Virus in Human Serum

Neutralization by antibodies and complement limits the effective dose and thus the therapeutic efficacy of oncolytic viruses after systemic application. We and others previously showed that pseudotyping of oncolytic rhabdoviruses such as maraba virus and vesicular stomatitis virus (VSV) with the lym...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Pipperger, Lisa, Koske, Iris, Wild, Nicole, Müllauer, Brigitte, Krenn, Daniela, Stoiber, Heribert, Wollmann, Guido, Kimpel, Janine, von Laer, Dorothee, Bánki, Zoltán
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2019
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714799/
https://ncbi.nlm.nih.gov/pubmed/31243134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00567-19
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