Xenoantigen-Dependent Complement-Mediated Neutralization of Lymphocytic Choriomeningitis Virus Glycoprotein-Pseudotyped Vesicular Stomatitis Virus in Human Serum

Neutralization by antibodies and complement limits the effective dose and thus the therapeutic efficacy of oncolytic viruses after systemic application. We and others previously showed that pseudotyping of oncolytic rhabdoviruses such as maraba virus and vesicular stomatitis virus (VSV) with the lym...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Pipperger, Lisa, Koske, Iris, Wild, Nicole, Müllauer, Brigitte, Krenn, Daniela, Stoiber, Heribert, Wollmann, Guido, Kimpel, Janine, von Laer, Dorothee, Bánki, Zoltán
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714799/
https://ncbi.nlm.nih.gov/pubmed/31243134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00567-19
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