Xenoantigen-Dependent Complement-Mediated Neutralization of Lymphocytic Choriomeningitis Virus Glycoprotein-Pseudotyped Vesicular Stomatitis Virus in Human Serum

Neutralization by antibodies and complement limits the effective dose and thus the therapeutic efficacy of oncolytic viruses after systemic application. We and others previously showed that pseudotyping of oncolytic rhabdoviruses such as maraba virus and vesicular stomatitis virus (VSV) with the lym...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Pipperger, Lisa, Koske, Iris, Wild, Nicole, Müllauer, Brigitte, Krenn, Daniela, Stoiber, Heribert, Wollmann, Guido, Kimpel, Janine, von Laer, Dorothee, Bánki, Zoltán
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2019
Soggetti:
Vaccines and Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714799/
https://ncbi.nlm.nih.gov/pubmed/31243134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00567-19
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