Xenoantigen-Dependent Complement-Mediated Neutralization of Lymphocytic Choriomeningitis Virus Glycoprotein-Pseudotyped Vesicular Stomatitis Virus in Human Serum

Neutralization by antibodies and complement limits the effective dose and thus the therapeutic efficacy of oncolytic viruses after systemic application. We and others previously showed that pseudotyping of oncolytic rhabdoviruses such as maraba virus and vesicular stomatitis virus (VSV) with the lym...

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Bibliographic Details
Published in:J Virol
Main Authors: Pipperger, Lisa, Koske, Iris, Wild, Nicole, Müllauer, Brigitte, Krenn, Daniela, Stoiber, Heribert, Wollmann, Guido, Kimpel, Janine, von Laer, Dorothee, Bánki, Zoltán
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2019
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714799/
https://ncbi.nlm.nih.gov/pubmed/31243134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00567-19
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