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Xenoantigen-Dependent Complement-Mediated Neutralization of Lymphocytic Choriomeningitis Virus Glycoprotein-Pseudotyped Vesicular Stomatitis Virus in Human Serum

Neutralization by antibodies and complement limits the effective dose and thus the therapeutic efficacy of oncolytic viruses after systemic application. We and others previously showed that pseudotyping of oncolytic rhabdoviruses such as maraba virus and vesicular stomatitis virus (VSV) with the lym...

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Foilsithe in:J Virol
Main Authors: Pipperger, Lisa, Koske, Iris, Wild, Nicole, Müllauer, Brigitte, Krenn, Daniela, Stoiber, Heribert, Wollmann, Guido, Kimpel, Janine, von Laer, Dorothee, Bánki, Zoltán
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714799/
https://ncbi.nlm.nih.gov/pubmed/31243134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00567-19
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