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The nonepigenetic role for small molecule histone deacetylase inhibitors in the regulation of cardiac function

Eight million US adults are projected to suffer from heart failure (HF) by 2030. Of concern, 5-year mortality rates following HF diagnosis approximate 40%. Small molecule histone deacetylase (HDAC) inhibitors have demonstrated efficacy for the treatment and reversal of HF. Historically, HDACs were s...

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Bibliographic Details
Published in:Future Med Chem
Main Authors: Romanick, Samantha S, Ferguson, Bradley S
Format: Artigo
Language:Inglês
Published: Future Science Ltd 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714070/
https://ncbi.nlm.nih.gov/pubmed/31161804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc-2018-0311
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