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The nonepigenetic role for small molecule histone deacetylase inhibitors in the regulation of cardiac function

Eight million US adults are projected to suffer from heart failure (HF) by 2030. Of concern, 5-year mortality rates following HF diagnosis approximate 40%. Small molecule histone deacetylase (HDAC) inhibitors have demonstrated efficacy for the treatment and reversal of HF. Historically, HDACs were s...

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Pubblicato in:Future Med Chem
Autori principali: Romanick, Samantha S, Ferguson, Bradley S
Natura: Artigo
Lingua:Inglês
Pubblicazione: Future Science Ltd 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714070/
https://ncbi.nlm.nih.gov/pubmed/31161804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc-2018-0311
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