Crystal Structure of the Human Cannabinoid Receptor CB2

The cannabinoid receptor CB2 is predominately expressed in the immune system and selective modulation of CB2 without the psychoactivity of CB1 has therapeutic potential in inflammatory, fibrotic and neurodegenerative diseases. Here we report the crystal structure of human CB2 in complex with a ratio...

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發表在:Cell
Main Authors: Li, Xiaoting, Hua, Tian, Vemuri, Kiran, Ho, Jo-Hao, Wu, Yiran, Wu, Lijie, Popov, Petr, Benchama, Othman, Zvonok, Nikolai, Locke, K’ara, Qu, Lu, Han, Gye Won, Iyer, Malliga R., Cinar, Resat, Coffey, Nathan J., Wang, Jingjing, Wu, Meng, Katritch, Vsevolod, Zhao, Suwen, Kunos, George, Bohn, Laura M., Makriyannis, Alexandros, Stevens, Raymond C., Liu, Zhi-Jie
格式: Artigo
語言:Inglês
出版: 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6713262/
https://ncbi.nlm.nih.gov/pubmed/30639103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.12.011
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