A rapid and sensitive UPLC-MS/MS method for the determination of flibanserin in rat plasma: application to a pharmacokinetic study

BACKGROUND: In this work, we aim to develop and validate a fast, simple, and sensitive method for the quantitative determination of flibanserin and the exploration of its pharmacokinetics. METHODS: Ultra-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) was the method of choic...

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Publicado en:BMC Chem
Autores principales: He, Long, You, Wenting, Wang, Sa, Jiang, Tian, Chen, Caiming
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer International Publishing 2019
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6710871/
https://ncbi.nlm.nih.gov/pubmed/31463480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-019-0620-9
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