UPLC–MS-MS Determination of Dihydrocodeine in Human Plasma and Its Application to a Pharmacokinetic Study

A sensitive and rapid ultra performance liquid chromatography tandem mass spectrometry (UPLC–MS-MS) method was developed to determine dihydrocodeine (DHC) in human plasma using diazepam as the internal standard (IS). Sample preparation was accomplished through a liquid–liquid extraction procedure wi...

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Bibliografiske detaljer
Udgivet i:J Chromatogr Sci
Main Authors: Zhang, Wei-min, Duan, Yan-pei, Li, Wei, Qiu, Jian-fei, Zhang, Zhi-yin
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Liquid Chromatography
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4885392/
https://ncbi.nlm.nih.gov/pubmed/26689716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/chromsci/bmv188
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