Biopharmaceutical and pharmacokinetic characterization of matrine as determined by a sensitive and robust UPLC–MS/MS method

The purpose of this research was to develop a sensitive and reproducible UPLC–MS/MS method to analyze matrine, an anticancer compound, and to use it to investigate its biopharmaceutical and pharmacokinetic behaviors in rats. A sensitive and fast UPLC–MS/MS method was successfully applied to determin...

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Detaylı Bibliyografya
Asıl Yazarlar: Yang, Zhen, Gao, Song, Yin, Taijun, Kulkarni, Kaustubh H., Teng, Yang, You, Ming, Hu, Ming
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859310/
https://ncbi.nlm.nih.gov/pubmed/20034755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2009.11.020
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