RIPK2-Mediated Autophagy and Negatively Regulated ROS-NLRP3 Inflammasome Signaling in GMCs Stimulated with High Glucose

BACKGROUND: Hyperglycemia plays a vital role in diabetic nephropathy (DN); autophagy and its potential upregulator receptor-interacting protein kinase 2 (RIPK2) are associated with ROS, which play a potential role in regulating NLRP3, and may be involved in inflammation in DN. AIM: In this study, we...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Mediators Inflamm
Hauptverfasser: Gao, Chenlin, Chen, Jiao, Fan, Fang, Long, Yang, Tang, Shi, Jiang, Chunxia, Wang, Jiying, Xu, Youhua, Xu, Yong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6710801/
https://ncbi.nlm.nih.gov/pubmed/31485193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/6207563
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge