RIPK2-Mediated Autophagy and Negatively Regulated ROS-NLRP3 Inflammasome Signaling in GMCs Stimulated with High Glucose

BACKGROUND: Hyperglycemia plays a vital role in diabetic nephropathy (DN); autophagy and its potential upregulator receptor-interacting protein kinase 2 (RIPK2) are associated with ROS, which play a potential role in regulating NLRP3, and may be involved in inflammation in DN. AIM: In this study, we...

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Publicat a:Mediators Inflamm
Autors principals: Gao, Chenlin, Chen, Jiao, Fan, Fang, Long, Yang, Tang, Shi, Jiang, Chunxia, Wang, Jiying, Xu, Youhua, Xu, Yong
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6710801/
https://ncbi.nlm.nih.gov/pubmed/31485193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/6207563
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