High Glucose and Lipopolysaccharide Prime NLRP3 Inflammasome via ROS/TXNIP Pathway in Mesangial Cells

While inflammation is considered a central component in the development in diabetic nephropathy, the mechanism remains unclear. The NLRP3 inflammasome acts as both a sensor and a regulator of the inflammatory response. The NLRP3 inflammasome responds to exogenous and endogenous danger signals, resul...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Diabetes Res
Auteurs principaux: Feng, Hong, Gu, Junling, Gou, Fang, Huang, Wei, Gao, Chenlin, Chen, Guo, Long, Yang, Zhou, Xueqin, Yang, Maojun, Liu, Shuang, Lü, Shishi, Luo, Qiaoyan, Xu, Yong
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736396/
https://ncbi.nlm.nih.gov/pubmed/26881256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/6973175
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