High Glucose and Lipopolysaccharide Prime NLRP3 Inflammasome via ROS/TXNIP Pathway in Mesangial Cells

While inflammation is considered a central component in the development in diabetic nephropathy, the mechanism remains unclear. The NLRP3 inflammasome acts as both a sensor and a regulator of the inflammatory response. The NLRP3 inflammasome responds to exogenous and endogenous danger signals, resul...

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Detalhes bibliográficos
Publicado no:J Diabetes Res
Main Authors: Feng, Hong, Gu, Junling, Gou, Fang, Huang, Wei, Gao, Chenlin, Chen, Guo, Long, Yang, Zhou, Xueqin, Yang, Maojun, Liu, Shuang, Lü, Shishi, Luo, Qiaoyan, Xu, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736396/
https://ncbi.nlm.nih.gov/pubmed/26881256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/6973175
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