FBW7 Regulates the Autophagy Signal in Mesangial Cells Induced by High Glucose

AIMS: Abnormal regulation of autophagy participates in the development of diabetic nephropathy. mTOR is the most common negative regulator of the autophagy signaling pathway. FBW7 constitutes the SCF (Skp1–Cullin1–F-box protein) recognition subunit of E3 ubiquitin ligase, and mTOR is a substrate of...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Gao, Chenlin, Fan, Fang, Chen, Jiao, Long, Yang, Tang, Shi, Jiang, Chunxia, Xu, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6500712/
https://ncbi.nlm.nih.gov/pubmed/31119177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/6061594
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