CYLD Deubiquitinase Negatively Regulates High Glucose-Induced NF-κB Inflammatory Signaling in Mesangial Cells

Nuclear factor-kappa B (NF-κB) is the key part of multiple signal transduction of inflammation in the pathogenesis of diabetic nephropathy (DN). The ubiquitin-proteasome system is extensively involved in the regulation of the NF-κB pathway. Cylindromatosis (CYLD) has deubiquitinase activity and acts...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Li, Yanhui, Huang, Wei, Xu, Youhua, Zhou, Luping, Liang, Yaling, Gao, Chenlin, Long, Yang, Xu, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5702419/
https://ncbi.nlm.nih.gov/pubmed/29259980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/3982906
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