PCB118 Induces Inflammation of Islet Beta Cells via Activating ROS-NLRP3 Inflammasome Signaling

BACKGROUND: Diabetes mellitus is a clinical syndrome caused by genetic and environmental factors. Growing evidence suggests that exposure to environmental endocrine disruptors and activation of NLRP3 inflammasome signaling play a vital role in diabetes. However, it is unclear how PCB118, a common en...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Jiang, Chunxia, Wang, Yuping, Guo, Man, Long, Yang, Chen, Jiao, Fan, Fang, Tang, Shi, Xu, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8147541/
https://ncbi.nlm.nih.gov/pubmed/34055976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/5522578
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