Phase Ib Trial To Evaluate the Safety and Pharmacokinetics of Multiple Ascending Doses of Filociclovir (MBX-400, Cyclopropavir) in Healthy Volunteers

Filociclovir (MBX-400, cyclopropavir) is an antiviral agent with activity against cytomegalovirus (CMV). A phase 1, double-blind, randomized, placebo-controlled (3:1 ratio), single-center, multiple-ascending-dose trial was conducted to assess the safety, tolerability, and pharmacokinetics of filocic...

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書目詳細資料
發表在:Antimicrob Agents Chemother
Main Authors: Rouphael, Nadine G., Hurwitz, Selwyn J., Hart, Mari, Beck, Allison, Anderson, Evan J., Deye, Gregory, Osborn, Blaire, Cai, Shu Yi, Focht, Chris, Amegashie, Cyrille, Bowlin, Terry L., Brooks, Jennifer, Mulligan, Mark J.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2019
主題:
Antiviral Agents
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6709474/
https://ncbi.nlm.nih.gov/pubmed/31285228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00717-19
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