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SERCA2a tyrosine nitration coincides with impairments in maximal SERCA activity in left ventricles from tafazzin‐deficient mice
The sarco/endoplasmic reticulum Ca(2+)‐ATPase (SERCA) is imperative for normal cardiac function regulating both muscle relaxation and contractility. SERCA2a is the predominant isoform in cardiac muscles and is inhibited by phospholamban (PLN). Under conditions of oxidative stress, SERCA2a may also b...
Gespeichert in:
| Veröffentlicht in: | Physiol Rep |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6708055/ https://ncbi.nlm.nih.gov/pubmed/31444868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14215 |
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