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Elevated whole muscle phosphatidylcholine: phosphatidylethanolamine ratio coincides with reduced SERCA activity in murine overloaded plantaris muscles

BACKGROUND: An increase in phosphatidylcholine:phosphatidylethanolamine (PC:PE) and a decrease in fatty acyl chain length, monounsaturated:polyunsaturated (MUFA:PUFA) fatty acyl ratio reduces SERCA activity in liposomes and in mouse models of obesity and muscular dystrophy. We have previously shown...

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Veröffentlicht in:Lipids Health Dis
Hauptverfasser: Fajardo, Val A., Mikhaeil, John S., Leveille, Cameron F., Tupling, A. Russell, LeBlanc, Paul J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5851149/
https://ncbi.nlm.nih.gov/pubmed/29534725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-018-0687-7
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