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Substantial Decrease in Plasmalogen in the Heart Associated with Tafazzin Deficiency
Tafazzin is the mitochondrial enzyme that catalyzes transacylation between a phospholipid and a lysophospholipid in remodeling. Mutations in tafazzin cause Barth syndrome, a potentially life-threatening disease with the major symptom of cardiomyopathy. In the tafazzin-deficient heart, cardiolipin (C...
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| Pubblicato in: | Biochemistry |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5893435/ https://ncbi.nlm.nih.gov/pubmed/29557170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00042 |
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