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Substantial Decrease in Plasmalogen in the Heart Associated with Tafazzin Deficiency

Tafazzin is the mitochondrial enzyme that catalyzes transacylation between a phospholipid and a lysophospholipid in remodeling. Mutations in tafazzin cause Barth syndrome, a potentially life-threatening disease with the major symptom of cardiomyopathy. In the tafazzin-deficient heart, cardiolipin (C...

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Detalles Bibliográficos
Publicado en:Biochemistry
Main Authors: Kimura, Tomohiro, Kimura, Atsuko K., Ren, Mindong, Berno, Bob, Xu, Yang, Schlame, Michael, Epand, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5893435/
https://ncbi.nlm.nih.gov/pubmed/29557170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00042
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