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The Basis for Acyl Specificity in the Tafazzin Reaction

Tafazzin is a mitochondrial enzyme that transfers fatty acids from phospholipids to lysophospholipids. Mutations in tafazzin cause abnormal molecular species of cardiolipin and the clinical phenotype of Barth syndrome. However, the mechanism by which tafazzin creates acyl specificity has been contro...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Schlame, Michael, Xu, Yang, Ren, Mindong
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392692/
https://ncbi.nlm.nih.gov/pubmed/28202545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.769182
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