IGF-1R Reduction Triggers Neuroprotective Signaling Pathways in Spinal Muscular Atrophy Mice

Spinal muscular atrophy (SMA) is a neuromuscular disease characterized by the selective loss of spinal motor neurons due to the depletion of the survival of motor neuron (SMN) protein. No therapy is currently available for SMA, which represents the leading genetic cause of death in childhood. In the...

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Publicado no:J Neurosci
Main Authors: Biondi, Olivier, Branchu, Julien, Ben Salah, Amina, Houdebine, Léo, Bertin, Lise, Chali, Farah, Desseille, Céline, Weill, Laure, Sanchez, Gabriel, Lancelin, Camille, Aïd, Saba, Lopes, Philippe, Pariset, Claude, Lécolle, Sylvie, Côté, Jocelyn, Holzenberger, Martin, Chanoine, Christophe, Massaad, Charbel, Charbonnier, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705454/
https://ncbi.nlm.nih.gov/pubmed/26311784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0608-15.2015
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