Physical exercise reduces cardiac defects in type 2 spinal muscular atrophy-like mice

Spinal muscular atrophy (SMA), the leading genetic cause of death in infants worldwide, is due to the misexpression of the survival of motor neuron protein, causing death of motor neurons. Several clinical symptoms suggested that, in addition to motor neurons, the autonomic nervous systems could be...

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Main Authors: Biondi, Olivier, Lopes, Philippe, Desseille, Céline, Branchu, Julien, Chali, Farah, Salah, Amina Ben, Pariset, Claude, Chanoine, Christophe, Charbonnier, Frédéric
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2012
Teme:
Neuroscience: Neurobiology of Disease
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528999/
https://ncbi.nlm.nih.gov/pubmed/22930275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.238196
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