Shift from Extracellular Signal-Regulated Kinase to AKT/cAMP Response Element-Binding Protein Pathway Increases Survival-Motor-Neuron Expression in Spinal-Muscular-Atrophy-Like Mice and Patient Cells

Spinal muscular atrophy (SMA), a recessive neurodegenerative disease, is characterized by the selective loss of spinal motor neurons. No available therapy exists for SMA, which represents one of the leading genetic causes of death in childhood. SMA is caused by a mutation of the survival-of-motor-ne...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Neurosci
Hlavní autoři: Branchu, Julien, Biondi, Olivier, Chali, Farah, Collin, Thibault, Leroy, Felix, Mamchaoui, Kamel, Makoukji, Joelle, Pariset, Claude, Lopes, Philippe, Massaad, Charbel, Chanoine, Christophe, Charbonnier, Frédéric
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2013
Témata:
Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6704952/
https://ncbi.nlm.nih.gov/pubmed/23467345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2728-12.2013
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky