WTAP facilitates progression of hepatocellular carcinoma via m6A-HuR-dependent epigenetic silencing of ETS1

BACKGROUND: N6-methyladenosine (m6A) methylation, a well-known modification with new epigenetic functions, has been reported to participate in the tumorigenesis of hepatocellular carcinoma (HCC), providing novel insights into the molecular pathogenesis of this disease. However, as the key component...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cancer
Hauptverfasser: Chen, Yunhao, Peng, Chuanhui, Chen, Junru, Chen, Diyu, Yang, Beng, He, Bin, Hu, Wendi, Zhang, Yanpeng, Liu, Hua, Dai, Longfei, Xie, Haiyang, Zhou, Lin, Wu, Jian, Zheng, Shusen
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6704583/
https://ncbi.nlm.nih.gov/pubmed/31438961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-019-1053-8
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