ALKBH5 suppresses malignancy of hepatocellular carcinoma via m(6)A-guided epigenetic inhibition of LYPD1

BACKGROUND: N6-methyladenosine (m(6)A) modification is an emerging layer of epigenetic regulation which is widely implicated in the tumorigenicity of hepatocellular carcinoma (HCC), offering a novel perspective for investigating molecular pathogenesis of this disease. The role of AlkB homolog 5 (ALK...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Chen, Yunhao, Zhao, Yanchun, Chen, Junru, Peng, Chuanhui, Zhang, Yanpeng, Tong, Rongliang, Cheng, Qiyang, Yang, Beng, Feng, Xiaode, Lu, Yuejie, Xie, Haiyang, Zhou, Lin, Wu, Jian, Zheng, Shusen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7416417/
https://ncbi.nlm.nih.gov/pubmed/32772918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-020-01239-w
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