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WTAP facilitates progression of hepatocellular carcinoma via m6A-HuR-dependent epigenetic silencing of ETS1

BACKGROUND: N6-methyladenosine (m6A) methylation, a well-known modification with new epigenetic functions, has been reported to participate in the tumorigenesis of hepatocellular carcinoma (HCC), providing novel insights into the molecular pathogenesis of this disease. However, as the key component...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Chen, Yunhao, Peng, Chuanhui, Chen, Junru, Chen, Diyu, Yang, Beng, He, Bin, Hu, Wendi, Zhang, Yanpeng, Liu, Hua, Dai, Longfei, Xie, Haiyang, Zhou, Lin, Wu, Jian, Zheng, Shusen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6704583/
https://ncbi.nlm.nih.gov/pubmed/31438961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-019-1053-8
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