High-metastatic cancer cells derived exosomal miR92a-3p promotes epithelial-mesenchymal transition and metastasis of low-metastatic cancer cells by regulating PTEN/Akt pathway in hepatocellular carcinoma

Exosomes play an important role in intercellular communication and metastatic progression of hepatocellular carcinoma (HCC). However, cellular communication between heterogeneous HCC cells with different metastatic potentials and the resultant cancer progression are not fully understood in HCC. Here...

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Pubblicato in:Oncogene
Autori principali: Yang, Beng, Feng, Xiaode, Liu, Hua, Tong, Rongliang, Wu, Jingbang, Li, Changbiao, Yu, Hanxi, Chen, Yunhao, Cheng, Qiyang, Chen, Junru, Cai, Xianlei, Wu, Wenxuan, Lu, Yuejie, Hu, Jiating, Liang, Kejiong, Lv, Zhen, Wu, Jian, Zheng, Shusen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7561497/
https://ncbi.nlm.nih.gov/pubmed/32917956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01450-5
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