High-metastatic cancer cells derived exosomal miR92a-3p promotes epithelial-mesenchymal transition and metastasis of low-metastatic cancer cells by regulating PTEN/Akt pathway in hepatocellular carcinoma

Exosomes play an important role in intercellular communication and metastatic progression of hepatocellular carcinoma (HCC). However, cellular communication between heterogeneous HCC cells with different metastatic potentials and the resultant cancer progression are not fully understood in HCC. Here...

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Publicat a:Oncogene
Autors principals: Yang, Beng, Feng, Xiaode, Liu, Hua, Tong, Rongliang, Wu, Jingbang, Li, Changbiao, Yu, Hanxi, Chen, Yunhao, Cheng, Qiyang, Chen, Junru, Cai, Xianlei, Wu, Wenxuan, Lu, Yuejie, Hu, Jiating, Liang, Kejiong, Lv, Zhen, Wu, Jian, Zheng, Shusen
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7561497/
https://ncbi.nlm.nih.gov/pubmed/32917956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01450-5
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