High-metastatic cancer cells derived exosomal miR92a-3p promotes epithelial-mesenchymal transition and metastasis of low-metastatic cancer cells by regulating PTEN/Akt pathway in hepatocellular carcinoma

Exosomes play an important role in intercellular communication and metastatic progression of hepatocellular carcinoma (HCC). However, cellular communication between heterogeneous HCC cells with different metastatic potentials and the resultant cancer progression are not fully understood in HCC. Here...

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Veröffentlicht in:Oncogene
Hauptverfasser: Yang, Beng, Feng, Xiaode, Liu, Hua, Tong, Rongliang, Wu, Jingbang, Li, Changbiao, Yu, Hanxi, Chen, Yunhao, Cheng, Qiyang, Chen, Junru, Cai, Xianlei, Wu, Wenxuan, Lu, Yuejie, Hu, Jiating, Liang, Kejiong, Lv, Zhen, Wu, Jian, Zheng, Shusen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7561497/
https://ncbi.nlm.nih.gov/pubmed/32917956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01450-5
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