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Protein amounts of the MYC transcription factor determine germinal center B cell division capacity
High affinity B cell selection in the germinal center (GC) is governed by signals delivered by follicular helper T cells (Tfh) to B cells. Selected B cells undergo clonal expansion and affinity maturation in the GC dark zone in direct proportion to the amount of antigen they capture and present to T...
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| Veröffentlicht in: | Immunity |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6703930/ https://ncbi.nlm.nih.gov/pubmed/31350178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2019.06.013 |
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