Improving CNS Delivery to Brain Metastases by Blood-Tumor Barrier Disruption

Brain metastases encompass nearly 80% of all intracranial tumors. A late stage diagnosis confers a poor prognosis, with patients typically surviving less than two years. Poor survival can be equated to limited effective treatment modalities. One reason for the failure rates is the presence of the bl...

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Publicado en:Trends Cancer
Autores principales: Sprowls, Samuel A., Arsiwala, Tasneem A., Bumgarner, Jacob R., Shah, Neal, Lateef, Sundus S., Kielkowski, Brooke N., Lockman, Paul R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6703178/
https://ncbi.nlm.nih.gov/pubmed/31421906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2019.06.003
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