A Review of Mathematics Determining Solute Uptake at the Blood–Brain Barrier in Normal and Pathological Conditions

The blood–brain barrier (BBB) limits movement of solutes from the lumen of the brain microvascular capillary system into the parenchyma. The unidirectional transfer constant, K(in), is the rate at which transport across the BBB occurs for individual molecules. Single and multiple uptake experiments...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Sprowls, Samuel A., Saralkar, Pushkar, Arsiwala, Tasneem, Adkins, Christopher E., Blethen, Kathryn E., Pizzuti, Vincenzo J., Shah, Neal, Fladeland, Ross, Lockman, Paul R.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8160855/
https://ncbi.nlm.nih.gov/pubmed/34069733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13050756
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