Recent Advances in Blood–Brain Barrier Disruption as a CNS Delivery Strategy

The blood–brain barrier (BBB) is a complex functional barrier composed of endothelial cells, pericytes, astrocytic endfeets and neuronal cells. This highly organized complex express a selective permeability for molecules that bear, amongst other parameters, adequate molecular weight and sufficient l...

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Detalhes bibliográficos
Main Authors: Bellavance, Marc-André, Blanchette, Marie, Fortin, David
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2008
Assuntos:
Review Article/Themed Issue: Current Advances in CNS Delivery of Therapeutic Molecules Guest Editors: Jean-Michael Scherrman and
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2751463/
https://ncbi.nlm.nih.gov/pubmed/18446517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-008-9018-7
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