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Enantio- and Diastereoselective Synthesis of Functionalized Carbocycles by Cu-Catalyzed Borylative Cyclization of Alkynes with Ketones

A single-pot Cu-catalyzed enantio- and diastereoselective tandem hydroboration/borylative cyclization of alkynes with ketones for the synthesis of carbocycles is reported. The reaction proceeds via a desymmetrization and generates four contiguous stereocenters, including an all-carbon quaternary cen...

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書目詳細資料
發表在:Org Lett
Main Authors: Zanghi, Joseph M., Liu, Shuang, Meek, Simon J.
格式: Artigo
語言:Inglês
出版: 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6702961/
https://ncbi.nlm.nih.gov/pubmed/31199654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.9b01769
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