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Enantio- and Diastereoselective Synthesis of Hydroxy Bis(boronates) via Cu-Catalyzed Tandem Borylation/1,2-Addition

Catalytic enantioselective synthesis of 1-hydroxy-2,3-bisboronate esters through multicomponent borylation/1,2-addition is reported. Catalyst and substrates are readily available, form both a C–B and C–C bond, and generate up to three contiguous stereocenters. The reaction is tolerant of aryl, vinyl...

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Detalhes bibliográficos
Publicado no:ACS Catal
Main Authors: Green, Jacob C., Joannou, Matthew V., Murray, Stephanie A., Zanghi, Joseph M., Meek, Simon J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837064/
https://ncbi.nlm.nih.gov/pubmed/29520326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.7b01123
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