MALT1 Proteolytic Activity Suppresses Autoimmunity in a T Cell Intrinsic Manner

MALT1 is a central signaling component in innate and adaptive immunity by regulating NF-κB and other key signaling pathways in different cell types. Activities of MALT1 are mediated by its scaffold and protease functions. Because of its role in lymphocyte activation and proliferation, inhibition of...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Demeyer, Annelies, Skordos, Ioannis, Driege, Yasmine, Kreike, Marja, Hochepied, Tino, Baens, Mathijs, Staal, Jens, Beyaert, Rudi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6702287/
https://ncbi.nlm.nih.gov/pubmed/31474984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01898
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