MALT1-Deficient Mice Develop Atopic-Like Dermatitis Upon Aging

MALT1 plays an important role in innate and adaptive immune signaling by acting as a scaffold protein that mediates NF-κB signaling. In addition, MALT1 is a cysteine protease that further fine tunes proinflammatory signaling by cleaving specific substrates. Deregulated MALT1 activity has been associ...

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Bibliografske podrobnosti
izdano v:Front Immunol
Main Authors: Demeyer, Annelies, Van Nuffel, Elien, Baudelet, Griet, Driege, Yasmine, Kreike, Marja, Muyllaert, David, Staal, Jens, Beyaert, Rudi
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779721/
https://ncbi.nlm.nih.gov/pubmed/31632405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02330
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