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T-cell receptor-induced JNK activation requires proteolytic inactivation of CYLD by MALT1
The paracaspase mucosa-associated lymphoid tissue 1 (MALT1) is central to lymphocyte activation and lymphomagenesis. MALT1 mediates antigen receptor signalling to NF-κB by acting as a scaffold protein. Furthermore, MALT1 has proteolytic activity that contributes to optimal NF-κB activation by cleavi...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3101995/ https://ncbi.nlm.nih.gov/pubmed/21448133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.85 |
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