ZBP1/DAI Drives RIPK3-Mediated Cell Death Induced by Interferons in the Absence of RIPK1

Receptor-interacting protein kinase 1 (RIPK1) regulates cell fate and pro-inflammatory signaling downstream of multiple innate immune pathways, including those initiated by TNF-α, Toll-like Receptor (TLR) ligands, and Interferons (IFNs). Genetic ablation of Ripk1 results in perinatal lethality arisi...

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Vydáno v:J Immunol
Hlavní autoři: Ingram, Justin P., Thapa, Roshan J., Fisher, Amanda, Tummers, Bart, Zhang, Ting, Yin, Chaoran, Rodriguez, Diego, Guo, Hongyan, Lane, Rebecca, Williams, Riley, Slifker, Michael J., Basagoudanavar, Suresh H., Rall, Glenn F., Dillon, Christopher P., Green, Douglas R., Kaiser, William J., Balachandran, Siddharth
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6702065/
https://ncbi.nlm.nih.gov/pubmed/31358656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900216
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