ZBP1/DAI Drives RIPK3-Mediated Cell Death Induced by Interferons in the Absence of RIPK1

Receptor-interacting protein kinase 1 (RIPK1) regulates cell fate and pro-inflammatory signaling downstream of multiple innate immune pathways, including those initiated by TNF-α, Toll-like Receptor (TLR) ligands, and Interferons (IFNs). Genetic ablation of Ripk1 results in perinatal lethality arisi...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Ingram, Justin P., Thapa, Roshan J., Fisher, Amanda, Tummers, Bart, Zhang, Ting, Yin, Chaoran, Rodriguez, Diego, Guo, Hongyan, Lane, Rebecca, Williams, Riley, Slifker, Michael J., Basagoudanavar, Suresh H., Rall, Glenn F., Dillon, Christopher P., Green, Douglas R., Kaiser, William J., Balachandran, Siddharth
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6702065/
https://ncbi.nlm.nih.gov/pubmed/31358656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900216
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