Murine cytomegalovirus IE3‐dependent transcription is required for DAI/ZBP1‐mediated necroptosis

DNA‐dependent activator of interferon regulatory factors/Z‐DNA binding protein 1 (DAI/ZBP1) is a crucial sensor of necroptotic cell death induced by murine cytomegalovirus (MCMV) in its natural host. Here, we show that viral capsid transport to the nucleus and subsequent viral IE3‐dependent early tr...

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Pubblicato in:EMBO Rep
Autori principali: Sridharan, Haripriya, Ragan, Katherine B, Guo, Hongyan, Gilley, Ryan P, Landsteiner, Vanessa J, Kaiser, William J, Upton, Jason W
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538628/
https://ncbi.nlm.nih.gov/pubmed/28607035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201743947
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