Murine cytomegalovirus IE3‐dependent transcription is required for DAI/ZBP1‐mediated necroptosis

DNA‐dependent activator of interferon regulatory factors/Z‐DNA binding protein 1 (DAI/ZBP1) is a crucial sensor of necroptotic cell death induced by murine cytomegalovirus (MCMV) in its natural host. Here, we show that viral capsid transport to the nucleus and subsequent viral IE3‐dependent early tr...

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Enregistré dans:
Détails bibliographiques
Publié dans:EMBO Rep
Auteurs principaux: Sridharan, Haripriya, Ragan, Katherine B, Guo, Hongyan, Gilley, Ryan P, Landsteiner, Vanessa J, Kaiser, William J, Upton, Jason W
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2017
Sujets:
Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538628/
https://ncbi.nlm.nih.gov/pubmed/28607035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201743947
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