Species-independent contribution of ZBP1/DAI/DLM-1-triggered necroptosis in host defense against HSV1

Necroptosis complements apoptosis as a host defense pathway to stop virus infection. Herpes simplex virus shows a propensity to trigger necroptosis of mouse cells and mice even though cell death is blocked in human cells through UL39-encoded ICP6. This ribonucleotide reductase large subunit (R1) nuc...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Guo, Hongyan, Gilley, Ryan P., Fisher, Amanda, Lane, Rebecca, Landsteiner, Vanessa J., Ragan, Katherine B., Dovey, Cole M., Carette, Jan E., Upton, Jason W., Mocarski, Edward S., Kaiser, William J.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062522/
https://ncbi.nlm.nih.gov/pubmed/30050136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0868-3
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