Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules

DNA, whether it is microbe-derived or host-derived, evokes immune responses when exposed to the cytosol of a cell. We previously reported that DNA-dependent activator of IFN regulatory factors (DAI), also referred to as DLM-1/ZBP1, functions as a DNA sensor that activates the innate immune system. I...

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Detalhes bibliográficos
Main Authors: Wang, ZhiChao, Choi, Myoung Kwon, Ban, Tatsuma, Yanai, Hideyuki, Negishi, Hideo, Lu, Yan, Tamura, Tomohiko, Takaoka, Akinori, Nishikura, Kazuko, Taniguchi, Tadatsugu
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291118/
https://ncbi.nlm.nih.gov/pubmed/18375758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801295105
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