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Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules
DNA, whether it is microbe-derived or host-derived, evokes immune responses when exposed to the cytosol of a cell. We previously reported that DNA-dependent activator of IFN regulatory factors (DAI), also referred to as DLM-1/ZBP1, functions as a DNA sensor that activates the innate immune system. I...
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| Autores principales: | , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2291118/ https://ncbi.nlm.nih.gov/pubmed/18375758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801295105 |
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