Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis

Influenza A virus (IAV) is a lytic RNA virus that triggers receptor-interacting serine/threonine-protein kinase 3 (RIPK3)-mediated pathways of apoptosis and mixed lineage kinase domain-like pseudokinase (MLKL)-dependent necroptosis in infected cells. ZBP1 initiates RIPK3-driven cell death by sensing...

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Publicat a:Cell
Autors principals: Zhang, Ting, Yin, Chaoran, Boyd, David F., Quarato, Giovanni, Ingram, Justin P., Shubina, Maria, Ragan, Katherine B., Ishizuka, Takumi, Crawford, Jeremy Chase, Tummers, Bart, Rodriguez, Diego A., Xue, Jia, Peri, Suraj, Kaiser, William J., López, Carolina B., Xu, Yan, Upton, Jason W., Thomas, Paul G., Green, Douglas R., Balachandran, Siddharth
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7153753/
https://ncbi.nlm.nih.gov/pubmed/32200799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.02.050
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